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At the end of the day, its all about balance

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and oligodendroglial indicators oligodendrocyte transcription factor 2 (Olig2, 0.08 g/ml, 1:250, R&D Systems, goat AF2418), platelet-derived growth factor receptor alpha (PDGFR, 5 g/ml, 1:200, ThermoFisher Scientific, rabbit PA5-16571), aspartoacylase (ASPA, 2 g/ml, 1:500, EMD Millipore, rabbit ABN1698), and adenomatous polyposis coli (APC) clone (CC1, 0.2 g/ml, 1:500, ThermoFisher Scientific, mouse MA1-25884)

As for T1 always studied as a modulator of T cell responses, MS was considered by far a T cell-mediated autoimmune disease