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PMID: 2564253, DOI: 10.1152/ajpgi.1989.256.3.g482

Holmes, A., et al

The vascular endothelial growth factor (VEGF), the main modulator of the growth of new blood vessels, lost its angiogenic property in TRPC4 knockdown HRMECs cell culture, suggesting a role for TRPC4 as a modulator in retinal neovascularization (Song et al., 2015)

Underlying mechanisms are incompletely defined but include intraoperative and postoperative phenomena, such as inflammation, sympathetic activation and cardiac ischaemia, that combine to trigger atrial fibrillation, often in the presence of pre-existing factors, making the atria vulnerable to atrial fibrillation induction and maintenance