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In the absence of agonists, GPCRs may display different levels of constitutive activities

Deb Roy S., Saxena M., Bhomkar P.S., Pooggin M., Hohn T

Image formation by induced local interactions: examples employing nuclear magnetic resonance

2009;28(Suppl):446S

This epigenetic reprogramming extends to DNA, where 2HG heightening is strongly linked to the glioma CpG island methylator phenotype (G-CIMP) observed in grade II/III gliomas and glioblastomas