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IL-10, a critical anti-inflammatory cytokine, is produced by activated innate or adaptive immune system cells, primarily macrophages (Ip et al., 2017)

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Figure 2 Cellular Processes Linked to Redox Imbalance That Are Dysregulated in Als Protein Misfolding The presence of misfolded proteins is known to induce oxidative stress

Lifespan assays Manual lifespan assays were performed at 20 C on heat-inactivated OP50 bacteria, seeded onto NGM plates containing nystatin if otherwise stated