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CLSM images (Figure 7) revealed that 8-MOP encapsulated in dendrimers was able to penetrate into deep skin layers, epidermis and dermis, compared to standard formulation

Bioavailability and bioequivalence Bioavailability Bioavailability is defined as: the fraction (percentage) of an administered dose of unchanged medicine that reaches the blood stream (systemic circulation)

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Quantitative real-time PCR RNA was purified by using ReliaPrep RNA (Promega, WI, USA) and reverse transcription was performed using 1.5 g total RNA as template with the ImProm-II Reverse Transcription System (Promega, WI, USA)