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Multiple sequence alignment of the ChaC1 homologues from different phyla revealed that all the members contained the signature motif and catalytic glutamate residue confirming that the ChaC family of proteins belongs to the family of GCTs (supplementary Fig S3 online)

In: Poretsky L, editor

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Evaluation of oxidative stress in autism: defective antioxidant enzymes and increased lipid peroxidation

Interestingly, the greatest risk reduction was conveyed by drugs affecting T cells such as the inosine monophosphate dehydrogenase inhibitors, azathioprine and mycophenolat mofetil (106), while a protective effect was revealed for corticosteroids