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The most adverse effects were observed in the kidney due to a significant increase in the inflammatory biomarkers MCP-1 and IL-6 at a dose of 100 mg/kg bw/day and TNF-, resistin and PAI-1 were significantly increased at a dose of 100 mg/kg bw/day, 100 mg/kg bw/day, and 200 mg/kg bw/day, respectively (Figure 5)

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Regions were characterized and defined based on nuclear morphology and presence or absence of mitotic/meiotic structures as follows: (1) Mitotic: round-shape interphase nuclei with evenly distributed chromatin and defined nucleolus and the presence of mitotic metaphases and anaphase

In vivo metabolism and genotoxic effects of nitrated polycyclic aromatic hydrocarbons

447 The liver of patients with Wilson disease contains excess copper and a large amount of iron