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and the research by Bowers et al., from 2004 suggest that the peptides may induce a significant stimulation of hGH synthesis in pituitary cells that may then prove to be sufficient to induce IGF-1 synthesis in nearby cell cultures

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Translational Relevance While preclinical studies are essential for understanding the mechanisms of action and potential therapeutic effects of Ipamrelin, the translation of these findings to human patients requires further clinical research