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R.RomeroGalloJ.et al

cADP-ribose, ADP-ribose, and nicotinic acid adenine dinucleotides are produced by NADases CD38 and CD157 in Ca2+ signaling and intercellular immunological communication (1,3)

This combinatorial approach may ultimately prove more flexible than the all-in-one triple-agonist strategy, because it allows each component to be dosed independently and titrated to individual response

& Mauck, R

To determine whether afatinib exhibited differing effects on stem-like HNSCC cells, we treated the indicated cell lines with various concentrations of afatinib for 24 h and examined cell survival by SRB assay