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The lower the RSI, the higher the activity of the hydrosoluble antioxidant protective systems in the serum [Margina et al., 2009]

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Catalytic bioswitch of platinum nanozymes: mechanistic insights of reactive oxygen species scavenging in the neurovascular unit

Three distinctive cellular protective mechanisms against ferroptosis Studies have hitherto demonstrated that cells may have evolved at least three defense systems with different subcellular localizations, of which cytosol- and mitochondria-localized GPx4 confers the major protection against lipid peroxidation, while ferroptosis suppressor protein 1 (FSP1) acts mainly on the plasma membrane, and dihydroorotate dehydrogenase (DHODH) is a major defensive arm in mitochondria

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