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Explants treated with the extract (50400 g/ml) suppressed proteoglycan degradation by IL-1

Mechanism of regulation of intestinal epithelial tight junction proteins A crucial function of IECs is the maintenance of barrier integrity, which allows the permeability of essential ions, nutrients, and water but restricts the entry of bacterial toxins and pathogens 21

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These functional groups can influence the charge density and hydrophobicity of NPs (Nel et al., 2009