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Excess levels of free reactive iron cause tissue damage and oxidative cell death

Decreasing oxidative stress and increasing antioxidant ability may face the potent prospect of clinical application for improving the outcomes of hip fractures

: 400 (NK)

This suggests that NCOA4 in AD may be translocated to the cytoplasm, where it could induce the degradation of ferritin and increase sensitivity to ferroptosis [41]