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Figure 8 4 Discussion 4.1 Plant GPXs protect cells against cell death, just like animal GPX4s/PHGPX Pathogen infection induces oxidative stress in plants, leading to ROS accumulation that disrupts membrane integrity through lipid peroxidation (Keppler et al., 1989

Song Z, Jia G, Ma P, Cang S

Inflammation appears to lead to persistent changes in basal ganglia and DA function, as shown by lack of pleasure, fatigue, and psychomotor slowing

This alters neuronal membrane potential and OS states, ultimately leading to neuronal death [23, 48, 49]

Necrosis and fibrosis of the thyroid gland, particularly after iodide loading, is exacerbated by Se deficiency [76]