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We speculate that abnormal iron metabolism and gut microbiota dysbiosis can promote each other and play a synergistic role in promoting ferroptosis of chondrocytes

Brandes RP, Viedt C, Nguyen K, Beer S, Kreuzer J, Busse R et al

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Overall, resveratrol exerts multi-faceted anti-cancer effects by modulating tumor immunity (e.g., boosting cytotoxic T cells and NK cells), reversing drug resistance (via down-regulating EGFR and P-gp), inducing autophagy and ferroptosis, and arresting cell cycle progression while promoting apoptosis