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In our experience treating thousands of patients, small dose adjustments including holding at a lower dose longer or modifying escalation timing often determine whether someone tolerates therapy long enough to reach meaningful weight reduction

Patients with Lebers hereditary optic neuropathy should not receive B12 due to the risk of optic nerve damage

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Induration, the medical term for a hardened area under the skin, develops when the inflammatory response causes fluid accumulation and tissue thickening

It is whether the protocol around it, the cycle structure, the rest period, the sequencing with other compounds, and the biological fit with the patient, is designed correctly