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aurata (SAM-2 and SAF-1) samples were found most rich in nitrogenous compounds (13.7 and 8.7 mg/g, respectively) with creatinine (peak 75) as major form in both samples (47 mg/g)

Two predicted drugs (gemcitabine and cladribine) and one NO-based drug (diphenyleneiodonium) have a reported median IC 50 below 0.4 M in melanoma cell lines, this being comparable to known anti-melanoma drugs (Supplementary Fig

In contrast, an overdose of APAP causes hepatotoxicity by saturating the sulfation pathway and generating NAPQI that leads to a robust reaction between NAPQI and hepatic glutathione stores, which subsequently depletes glutathione (Xie et al., 2015)

miR-15a and miR16-1 are expressed at a higher level in the LECs of patients with cataracts compared with normal controls (77)

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