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Front Immunol (2018) 9:1127

[DOI] [PubMed] [Google Scholar] 28.Zhi X., Feng W., Rong Y., Liu R

Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits