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Gut integrity declines with age, a phenomenon sometimes called "leaky gut," where the tight junctions between intestinal epithelial cells loosen and allow bacterial products to enter systemic circulation, driving chronic low-grade inflammation

Reuterin has antimicrobial properties and undergoes chemical conjugation with dietary heterocyclic amines (HCAs)

Proc Natl Acad Sci 102:1364613651 Cheng C, Wang X, Dong Z, Shao C, Yang Y, Fang W, Fang C, Wang H, Yang M, Jiang L (2015) Aminopeptidase T of M29 family acts as a novel intracellular virulence factor for Listeria monocytogenes infection

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Our research suggests that MT1G promoting iron autophagy in GC cell lines can be a valuable new approach as a GC replacement therapy strategy