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In my clinic, I use ferrous aspartate with patients because I have found it that it does not upset the stomach or cause constipation the way other forms of iron can

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These dysfunctions may arise from impaired pyruvate dehydrogenase (PDH) function identified in muscle cells (390) and serum (184), as well as reduced plasma coenzyme Q10 (CoQ10) levels in ME/CFS blood and plasma (372, 391) that is inversely associated with fatigue severity (391)