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Methods: A comprehensive search was conducted across PubMed, Scopus, and Embase up to July 2024

Vigorous shaking destroys peptide structure through mechanical stress

A randomized multicenter phase II study comparing capecitabine with irinotecan or cisplatin in metastatic adenocarcinoma of the stomach or esophagogastric junction

The inhibitory compounds properties are fundamentally changed thus making them easier to treat

Among the membrane models utilized, micellar systems can be considered an interesting alternative to study the interactions of different compounds with membranes because of the relative simplicity of these systems, and therefore have been used with this purpose (13,20)