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Elevated levels of pro-inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-), generate massive amounts of reactive oxygen species (ROS)

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76 In clinical trials, up to 6.7% of patients had elevated CPK levels, and daptomycin-associated myopathy occurred in 2% to 14% of patients

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For instance, in a double-blinded randomized clinical trial, Maghbooli et al