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On physical exam, he was painful on palpation of all joints, and in his lower back as well

Well, further research as proven this to be true, though at first, this suggestion started as a myth

Colombo, L

Although the correlation between phosphatidylcholine remodeling and ferroptosis sensitivity is well recognized, whether the PC axis functions as an active mechanistic driver or merely reflects downstream metabolic remodeling remains under active investigation

Our recent study demonstrates the crosstalk between impaired mitochondrial metabolism and dynamics, oxidative stress, inflammation, and ASC malfunction, which suggests that pharmacological modulation of mitochondrial activity might benefit ASC immunomodulatory potential [23]