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On the other hand, overexpression of Sb9 is an important mechanism of immune evasion in diseases like cancers and viral infections

The mRNA-Based Innovative Strategy: Progress and Challenges

Tumor hypoxia-activated combinatorial nanomedicine triggers systemic antitumor immunity to effectively eradicate advanced breast cancer

This is consistent with the observed reversal of immune-related KEGG pathways

Both the PI3K/Akt and Ras/MAPK signaling will phosphorylate the proapoptotic protein BAD, causing inactivation due to cytoplasmic sequestration, which leads to enhanced platinum resistance by blocking apoptosis [114]