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A systematic review identified two small randomized, double-blind, placebo-controlled trials that found little evidence of a reduction in systolic or diastolic blood pressure following the administration of coenzyme Q 10 (100-200 mg/day) for three months (47)

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J Viral Hepat 19:353363 Huerga Encabo H, Traveset L, Argilaguet J, Angulo A, Nistal-Villan E, Jaiswal R, Escalante CR, Gekas C, Meyerhans A, Aramburu J, Lopez-Rodriguez C (2020) The transcription factor NFAT5 limits infection-induced type I interferon responses

Novel pharmacological agents and interventions in myocardial IRI Targeting innate and adaptive immunity: NLRP3-, SGLT- and PARP-inhibitors NLRP3 inhibitors are emerging as a new class of immunomodulatory compounds with potential relevance across multiple inflammatory and cardiometabolic conditions, and their therapeutic potential continues to expand as increasing preclinical and translational evidence clarifies their mechanisms of action