Delivery matters for some people Intramuscular injections deliver B12 directly into muscle, bypassing absorption problems
Sources Weight loss surgery (2025) NHS [accessed 27 October 2025] Tirzepatide for managing overweight and obesity (2024) NICE [accessed 27 October 2025] Bariatric Surgery Frequently Asked Questions (2025) NHS North Bristol [accessed 27 October 2025] Weight Loss Surgery Prices (2025) Ramsay Health [accessed 27 October 2025] Having an operation (surgery) (2024) NHS [accessed 27 October 2025] Dumping syndrome (2025) Mayo Clinic [accessed 27 October 2025]
We then highlight recent advances in pre-clinical and translational regenerative technologies that may address these challenges in cartilage restoration, and identify areas with the most pressing need for continued development
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