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One study found that blood levels of cytokines, including IL-6 and TNF-, were significantly higher in depressed patients than in healthy controls (202), and that these pro-inflammatory cytokines, especially IL-6, IL-1, and TNF-, promote the production of Th17, which has been implicated in depression and other CNS disorders closely associated with them (203)

This enzyme also regulates melanin production, making papaya a powerful tool for reducing pigmentation

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Reid MA, Wang W-I, Rosales KR, Welliver MX, Pan M, Kong M

Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age