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Description

Second, since HSL appears to be the only neutral cholesteryl ester hydrolase in adipose tissue, the inability to hydrolyze cholesteryl esters might reduce regulatory pools of cellular unesterified cholesterol (Figure 2B), which has been suggested to be a sensor linking adipose cell size to metabolism [24]

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[16] [18] There is insufficient evidence to determine the risk of adverse outcomes in human pregnancies, and thus, use during pregnancy should be guided by clinical judgment and individual risk assessment

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