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TABLE 3 Major mechanistic pathways mediating chronic constipation-depression comorbidity via the MGBA

The three primary factors that determine seawater density are pressure, temperature and salinity

Dynamic monitoring of metabolomics showed that the change of PA (28:0)/PA (32:1) ratio reflected the treatment response two weeks earlier than CRP, providing a new biomarker system for precise adjustment of treatment regimen (76, 79)