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2012;7(3):e33066

This is particularly an issue in pediatric populations, where tools for predicting drug efficacy and developmental toxicity are not well established

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In astrocytes, adrenaline is produced by monoamine oxidase, and a release of Ca 2+ from the endoplasmic reticulum happens after the activation of phospholipase C by adrenaline (Novikova et al., 2020)

Low Vit D levels perturb the immune homeostasis, favoring the spread of EBV-infected cells and thereby further exacerbating the aberrant immune response