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Additionally, CD36 facilitates the uptake of fatty acids, exacerbates intracellular lipid peroxidation, and pushes T cells toward ferroptosis, which is marked by reduced production of essential cytotoxic cytokines

It also has a role in wound healing

5a-5b, Extended Data Fig

Adapter proteins are used to transfer the signal - in the case of insulin IRS-1 (insulin receptor substrate)

To decipher the functional interactions between Keap1Nrf2 system and other oncogenic pathways is one of the most important assignments for the conquest of Nrf2-dependent cancers