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14.4 Treatment and Prevention of Glucocorticoid-Induced Osteoporosis The efficacy and safety of Reclast to prevent and treat glucocorticoid-induced osteoporosis (GIO) was assessed in a randomized, multicenter, double-blind, stratified, active controlled study of 833 men and women aged 18 to 85 years (mean age of 54.4 years) treated with greater than or equal to 7.5 mg/day oral prednisone (or equivalent)

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References MENOPAUSAL HOT FLASHES: MECHANISMS, ENDOCRINOLOGY, TREATMENT The 2023 nonhormone therapy position statement of The North American Menopause Society Menopause Hot Flashes and Molecular Mechanisms Modulated by Food-Derived Nutrients Yoga for menopausal symptomsA systematic review and meta-analysis The 2022 hormone therapy position statement of The North American Menopause Society Vasomotor Symptoms During Menopause: A Practical Guide on Current Treatments and Future Perspectives The circadian variation of sleep and alertness of postmenopausal women Core body temperature and circadian rhythm of hot flashes in menopausal women