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High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE

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Conversion of proIGF-1 to mature peptide requires the endoproteolytic cleavage of the E-domain by proprotein convertases, such as furin, which processes proproteins at highly conserved, unique pentabasic motif 3,4

Aminoglycoside antibiotics are still widely used for a variety of clinical applications

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