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This suggests that DNA methylation is not static but serves as a highly adaptable tool for epigenetic regulation (Smith and Meissner, 2013)

doi: 10.1038/s41583-020-0360-9 24

Characterization of microRNAs differentially expressed during bovine follicle development

These modifications reduce IGF-binding protein affinity, resulting in 2-3 times greater potency than native IGF-1 with a significantly extended half-life