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In murine models, NNMT knockdown did not induce the accumulation of NAM in livers and adipose tissues, nor did it cause significant alterations in the intracellular levels of NAD + in hepatocytes (Kraus et al., 2014

Research has shown that 40 to 90% of RLS cases have at least one first-degree relative with RLS

Side Effects and Safety Profile The extensive clinical development program for AOD-9604 included rigorous safety assessment across animal toxicology studies and human trials, providing a comprehensive understanding of the peptides safety profile