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Trends Pharmacol Sci 30:581591 Zhang P, Yang M, Chen C, Liu L, Wei X, Zeng S (2020) Toll-like receptor 4 (TLR4)/opioid receptor pathway crosstalk and impact on opioid analgesia, immune function, and gastrointestinal motility

Aerobic exercise improves synaptic-related proteins of diabetic rats by inhibiting FOXO1/NF-B/NLRP3 inflammatory signaling pathway and ameliorating PI3K/Akt insulin signaling pathway

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Sex, height and BMI score were included as fixed effects, while individual and study centre were included as random effects, with individual nested under the study centre