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Archived from the original on 12 May 2021

Also, intranasal delivery generally produces fewer systemic side effects due to reduced peripheral exposure

Summary: Vitamin B12 deficiency can cause recurrent mouth ulcers by impairing DNA synthesis and cell division in the rapidly renewing oral mucosa, making tissues vulnerable to damage and slow to heal

No long-term safety or efficacy data exists

Require diagnosis and monitoring: Some conditions (like high blood pressure, diabetes, or bacterial infections) need a professional diagnosis and ongoing monitoring