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doi: 10.3389/fendo.2022.925206 Received 21 April 2022 Accepted 30 May 2022 Published 28 June 2022 Volume 13 - 2022 Edited by Alfredo Ulloa-Aguirre, National Autonomous University of Mexico, Mexico Reviewed by Tatiana Fiordelisio, National Autonomous University of Mexico, Mexico

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In CKD, acetyl-CoA increase is related to lipid intermediates and lipid derivatives accumulation in the kidney (Szeto et al

Figure 2 Figure 3 Enzyme kinetics and inhibition studies The affinity-purified rSmGST showed parabolic change in enzyme activity when the enzyme was incubated at temperatures between 15 and 30C, and the optimum temperature for enzyme activity was 25C (Figure 4A)