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5B-C, none of the administration groups had an adverse effect on body weight or organ coefficients in mice

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Defined by hyperandrogenism, ovulatory dysfunction, insulin resistance, and chronic low-grade inflammation, PCOS, a common endocrine disorder in reproductive aged women causes irregular periods, infertility, excess androgens which collectively contributes toward long-term risks for serious conditions like type 2 diabetes, cardiovascular diseases, sleep apnea, depression, endometrial cancer and other reproductive complications underscoring the need for a comprehensive, multifaceted management strategy ( Figure 1 )

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acknowledges the EPSRC IRC Agile Early Warning Sensing Systems for Infectious Diseases and Antimicrobial Resistance (EP/R00529X/1), the Rosetrees Trust and the Department of Science, Innovation and Technology (DSIT) and the Royal Academy of Engineering under the Chair in Emerging Technologies programme (CiET2021\94)

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Histone H2AK119 mono-ubiquitination is essential for Polycomb-mediated transcriptional repression

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Int J MolSci

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