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Investigations CT scan of the chest, routine hematological study, sputum smear and culture for acid-fast bacilli, transbronchial lung biopsy, serum tumor markers, CT scan of the abdomen, MRI scan of the head, bone scintigraphy, lung function tests, blood gas analysis, pathological examination including hematoxylineosin staining and immunohistochemistry using chromogranin A, CD56 (neural cell adhesion molecule), and cytokeratin antibodies

In intestinal mucosa, Adrb2 deletion leads to an increased acute type 2 response, while Adrb2 activation (clenbuterol) notably inhibits ILC function in wild-type C57BL/6 (B6) mice (133)

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