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AFSCs exhibit expression of OCT4 and additional pluripotency markers, while preserving a rapid self-renewal capacity, maintaining a normal karyotype in long-term culture, and demonstrating low immunogenicity, which enables them to evade immune rejection

Early studies on Gly-His-Lys (GHK), first discovered in human plasma in the 1970s, demonstrated their ability to modulate gene expression, stimulate collagen synthesis, and accelerate wound healing, sparking broad interest in these bioactive molecules [23]

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[DOI] [PubMed] [Google Scholar] 249.Bramanti E., Onor M., Colombaioni L