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Appropriate duration and amount of ROS activity contribute to enhanced cellular functioning.80 However, an imbalance between amounts of ROS and antioxidant system products can result in oxidative damage.81 An imbalance between oxidative stress and antioxidants is also demonstrated in schizophrenia.8283 Several studies have reported excessive activity of oxidants84 and decreased antioxidants in patients with schizophrenia.85 Antioxidants consist of enzymatic and non-enzymatic materials

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Additionally, small-molecule chaperones, aldose reductase inhibitors, and protein aggregation inhibitors have also demonstrated potential in stabilizing or restoring lens protein structure and transparency