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Notably, despite constant progress in diverse aspects of natural drug monomers that protect against myocardial injury by activating the GSH system, great challenges remain in translating these compounds into future clinical pharmaceuticals

Dietary fiber protects against diabetic nephropathy through short-chain fatty acid-mediated activation of G protein-coupled receptors GPR43 and GPR109A

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Interestingly, GSH binds to a site similar to that in the AsA-bound structure but slightly away from Ser20 and towards the C-terminal domain (Fig

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