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Superimposed on these functional alterations are large numbers of passenger mutations, which are largely neutral but serve as molecular records of evolutionary history (76, 77)

The mcg delivered per spray is entirely dependent on the specific device used

Kornblau SM , Xu HJ, Smith TL, Beran M, Hester J, Benedict WF, Deisseroth AB

Increased inactivation of cisplatin by thiol-containing proteins is an important mechanism for tumor resistance, as showed for cervical cancers, osteosarcoma and glioblastoma cells 4,14,15,28