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Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2

EAS Congress Abstract book 80th European Atherosclerosis Society Congress, 2012, p 831

Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11

Based on this, and the fact that the gut modulates the metabolism and vice versa we evaluated the bacterial composition of the fecal gut microbiome in our PD mouse models (P479L rotenone experiment at day 32, Wt+R+E experiment at day 62, PARK2 vs Wt, PARK2+V vs PARK2+E, PARK2+V vs PARK2+R at day 32, and PARK2+R+E at day 54 experiment) using taxonomic marker gene sequencing (16S rRNA gene)