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Taken together, these findings indicate a potential relationship between protein oxidation, Ca 2+ regulation, and protein aggregation in ALS (Fig

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But now Northwestern Medicine scientists report results of the first in-human clinical trial in which they used a novel, skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy that was injected intravenously

Gler, S., Knemann, H., Wolfes, J., Gner, F., Ellermann, C., Rath, B., Frommeyer, G., Lange, P

Roman D, Kantarjian HM, Cortes JE, Borthakur G , Garcia-Manero G, Konopleva MY, DiNardo CD, Daver NG, Pemmaraju N, Kadia TM, Kornblau SM, Bose P, Andreeff M, Freireich EJ, Ravandi F, Aung FM