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Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology

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Smith, Br & Thompson, CD (2021)

The phenylarsenoxide group is the active moiety, imparting to GSAO its activity by crosslinking closely spaced protein thiols and forming a high affinity ring structure between its arsenic and the thiols ( FIGURE 3 4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid in its original form is essentially membrane impermeable

As expected, deleting the NTD and UBL domain in NUB1 1 175 did not affect its binding of FAM FAT10 (Fig