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We recently demonstrated that G6PD deficiency could be induced by either pharmacological inhibitors or G6PD siRNA, which impairs redox homeostasis and causes increased ROS levels and reduced GSH levels in monocytes and endothelial cells

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Houstis N, Rosen ED, Lander ES (2006) Reactive oxygen species have a causal role in multiple forms of insulin resistance

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Instead, only a partial identification of possible values of the effect of the policy can be recovered