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Cervical translaminar epidural steroid injection is an important part of this concept

Extensive evidence has demonstrated that TLR2/TLR4/NF-B pathway participates in the inflammatory response by promoting pro-inflammatory cytokines (TNF-, IL-1, IL-6, etc.) in DN (Wang et al., 2019)

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells