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They are given either in the muscle or through a vein

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Meanwhile, the ratio of GSR to GPX4 at the protein level was decreased in the A2ARi-treated group compared with the control group (Figure 3I), indicating that the GSSG accumulation upon A2ARi treatment is caused likely by an impaired capacity to recycle GSSG back to GSH

Sections were then washed and mounted with VECTASHIELD HardSet aqueous mountant (Vector Laboratories, Burlingame, CA, USA) and viewed using an Olympus FV1000 confocal laser scanning microscope (Olympus Corporation, Tokyo, Japan)

doi:10.1016/j.placenta.2014.12.009 [doi] Krotulski AJ, Garibay N, Walther D, Walton SE, Mohr ALA, Logan BK, Baumann MH., Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid, 5F-MDMB-PICA, in male rats, Neuropharmacology