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GxxxG motifs hold the TIM23 complex together

TGF-1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60c-src/EGFRY845 and Rho/ROCK signaling

This is especially difficult because under IL-13 conditions, upregulation of additional factors, including GPX4 and SLC7A11 (9), occur in an effort to maintain intracellular homeostasis